| dc.description.abstract | Objectives. This study aimed to analyze the epidemiological
and clinical characteristics of COVID-19 cases and investigate
risk factors including comorbidities and age in relation with
the clinical aftermath of COVID-19 in ICU admitted cases in
Bangladesh.
Methods. In this retrospective study, epidemiological and clini-
cal characteristics, complications, laboratory results, and clini-
cal management of the patients were studied from data obtained
from 168 individuals diagnosed with an advanced prognosis of
COVID-19 admitted in two hospitals in Bangladesh.
Results. Individuals in the study sample contracted COVID-19
through community transmission. 56.5% (n = 95) cases died in
intensive care units (ICU) during the study period. The median
age was 56 years and 79.2% (n = 134) were male. Typical clini-
cal manifestation included Acute respiratory distress syndrome
(ARDS) related complications (79.2%), fever (54.2%) and cough
(25.6%) while diabetes mellitus (52.4%), hypertension (41.1%)
and heart diseases (16.7%) were the conventional comorbidi-
ties. Clinical outcomes were detrimental due to comorbidities
rather than age and comorbid individuals over 50 were at more
risk. In the sample, oxygen saturation was low (< 95% SpO2)
in 135 patients (80.4%) and 158 (93.4%) patients received sup-
plemental oxygen. Identical biochemical parameters were found
in both deceased and surviving cases. Administration of anti-
viral drug Remdesivir and the glucocorticoid, Dexamethasone
increased the proportion of surviving patients slightly.
Conclusions. Susceptibility to developing critical illness due to
COVID-19 was found more in comorbid males. These atypical
patients require more clinical attention from the prospect of con-
trolling mortality rate in Bangladesh. | en_US |
